PDRN Polynucleotide Injections

An innovative regenerative aesthetic treatment designed to improve skin quality, smooth fine lines and restore radiance, without artificial results.

Located in Saint-Louis, on the border with Basel, the Biolaser aesthetic medical center offers PDRN polynucleotide injections, an advanced technology in regenerative aesthetic medicine. This innovative treatment naturally stimulates the skin to improve its texture, hydration and firmness, without adding volume.

The Biolaser center welcomes patients from Saint-Louis, Basel, Allschwil, Binningen, Lörrach, Weil am Rhein and Freiburg im Breisgau, seeking effective and natural solutions to improve their skin quality. Unlike traditional injections, polynucleotides work deep within the skin to repair tissue and reactivate biological processes.

polynucleotide injections

What are polynucleotides (PDRN)?

Polynucleotides (PDRN) are purified DNA fragments used in aesthetic medicine to stimulate the skin’s natural regeneration.

Once injected into the skin, they:

  • Stimulate fibroblasts to boost collagen and elastin production
  • Improve deep hydration
  • Promote skin tissue repair
  • Reduce inflammation and enhance overall skin quality

Unlike hyaluronic acid, polynucleotides do not add volume. Their action is biological: they act as true regeneration boosters.

Result: healthier, denser and visibly rejuvenated skin, without altering facial volume.

What are the benefits of polynucleotide injections?

Polynucleotide injections provide a global response to signs of fatigue and skin aging.

Main benefits:

  • Intense hydration: improved water retention
  • Improved texture: smoother, more even skin
  • Reduction of fine lines: natural collagen stimulation
  • Radiance boost: brighter, less dull complexion
  • Repair effect: faster healing and reduced inflammation

This treatment is particularly appreciated for its natural, progressive and non-frozen results.

In Saint-Louis, near Basel and Lörrach, polynucleotides are now an ideal alternative for those who want to improve skin quality without surgery.

Which areas can be treated with polynucleotides?

Polynucleotides can be used on different areas of the face and body, depending on your skin’s needs.

polynucleotide injections for eye contour

Most commonly treated areas:

  • Eye contour: dark circles, fine lines, thin or crepey skin
  • Full face: dull complexion, visible pores, loss of elasticity
  • Neck and décolleté: skin laxity
  • Acne scars: improved skin texture
  • Scalp (depending on protocol): support for hair density

The eye area is particularly suitable, as the skin is very thin and benefits more from a regenerative approach than volumizing treatments.

How does a polynucleotide session work at Biolaser in Saint-Louis?

At Biolaser, each PDRN treatment is performed by experienced doctors, in a safe medical environment with a fully personalized approach.

Treatment steps:

  1. Personalized consultation: skin analysis and tailored protocol
  2. Skin preparation: cleansing and disinfection
  3. Application of numbing cream: for optimal comfort
  4. Micro-injections: precise and targeted using very fine needles
  5. Massage and/or LED therapy: to enhance product diffusion and results
  • Session duration: 20 to 30 minutes
  • Downtime: none (immediate return to activities)
  • Side effects: mild redness or swelling, disappearing within hours

Close to Basel, Lörrach and Freiburg, Biolaser focuses on gentle techniques for natural and controlled results.

How many sessions are needed and what results can you expect?

Polynucleotide injections work progressively by stimulating the skin from within.

Results

  • First visible effects after 10 days
  • Optimal results after 3–4 weeks
  • Continuous improvement in skin quality

Recommended protocol

  • 3 sessions spaced 3–4 weeks apart
  • Maintenance every 4 to 6 months

Après la séance

  • Smoother, firmer skin
  • Brighter complexion
  • Reduction of fine lines and dark circles
  • Improved skin texture

Results remain natural, progressive and long-lasting, without altering facial features.

Polynucleotides (PDRN) vs hyaluronic acid: what’s the difference?

Polynucleotides and hyaluronic acid serve different purposes and can be complementary.

FeaturePolynucleotidesHyaluronic acid
Main actionRegenerativeVolumizing
EffectNatural & progressiveImmediate
TargetSkin quality & textureVolume & hydration
Best forEye area, thin skin, preventionCheekbones, lips, folds

These treatments are often combined for natural and harmonious results.

Who are polynucleotide injections for?

Polynucleotides are suitable for both men and women who want to improve skin quality without invasive procedures.

Ideal for:

  • Dehydrated, dull or tired skin
  • Early wrinkles and fine lines
  • Dark circles and eye contour
  • Acne scars or imperfections
  • Preventive anti-aging from age 30

Near Basel, Lörrach and Freiburg, this treatment is increasingly popular among patients seeking natural results.

Contraindications and precautions

Although polynucleotide injections are generally well tolerated, certain situations require caution:

Main contraindications:

  • Pregnancy and breastfeeding
  • Active autoimmune diseases
  • Skin infections (herpes, inflammatory acne, eczema)
  • Immunosuppressive or anticoagulant treatments
  • History of severe allergic reactions

A prior medical consultation is always carried out to ensure safety and adapt the protocol.

Why choose Biolaser in Saint-Louis for your polynucleotide injections?

Located near Basel, Biolaser is a leading center in regenerative aesthetic medicine in the region.

Our commitments:

  • Advanced regenerative technologies
  • Expert doctors in aesthetic injections
  • Personalized approach for each patient
  • Natural results without overcorrection

Ideally located for patients coming from:

  • Saint-Louis
  • Basel (Switzerland)
  • Allschwil / Binningen
  • Lörrach / Weil am Rhein
  • Freiburg im Breisgau

Price of PDRN polynucleotide injections

The price of PDRN polynucleotide injections depends on:

  • Treated area (face, eyes, neck…)
  • Number of sessions
  • Combination with other treatments

A personalized quote is provided during your first consultation.
Starting from €300 per syringe.

Polynucleotide injections in Saint-Louis, near Basel

PDRN polynucleotide injections represent a major advancement in aesthetic medicine, allowing natural and long-lasting skin regeneration.

At Biolaser in Saint-Louis, just minutes from Basel and close to Lörrach and Freiburg, our doctors provide a tailored approach to reveal your skin’s natural radiance.

Book your personalized consultation today.

Are polynucleotide injections painful?

The treatment is minimally painful thanks to very fine needles and a numbing cream.

How long do results last?

Results last several months, with maintenance recommended every 4–6 months.

Can polynucleotides be combined with other treatments?

Yes, they can be combined with skinboosters, mesotherapy or LED therapy.

Are there side effects?

Mild redness or swelling may occur but disappears quickly.

Polynucleotides or skinboosters: which one to choose?

Polynucleotides are more regenerative, while skinboosters are more hydrating. The two are complementary.